Plasma postdexamethasone cortisol levels in schizoaffective disorder

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Plasma postdexamethasone cortisol levels in schizoaffective disorder.

The degree of hypothalamic-pituitary-adrenal (HPA) axis dysregulation in depressed patients with schizoaffective disorder was compared to that seen in patients with major depressive disorder with and without delusional features. The frequency of nonsuppression to dexamethasone was similar for all three diagnostic groups. Maximum postdexamethasone plasma cortisol was greater for delusional depre...

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Postdexamethasone plasma cortisol and beta-endorphin levels in depression: relationship to severity of illness.

The hypothalamic-pituitary-adrenal (HPA) axis is dysregulated in many patients with depression, probably at all levels of the axis. To determine if HPA dysregulation is associated with severity of depression, we studied a group of 66 patients with major depressive disorder. Each patient underwent a pretreatment Dexamethasone Suppression Test, with plasma postdexamethasone cortisol determination...

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ژورنال

عنوان ژورنال: Psychiatry Research

سال: 1988

ISSN: 0165-1781

DOI: 10.1016/0165-1781(88)90085-6